IBX/I2-mediated oxidation of alkenes and alkynes in water: a facile synthesis of α-iodoketones
✍ Scribed by Jhillu S. Yadav; Basi V. Subba Reddy; Ashutosh P. Singh; Ashok K. Basak
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- French
- Weight
- 176 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0040-4039
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A Facile Synthesis of α-Iodo-β-nitroalkenes from Alkynes Using I 2 /NO 3 -or KI/NO 3 -. -The title synthesis is safer and more convenient than that with the known reagent I 2 /N 2 O 4 . The reaction can be applied to an internal alkyne as well as a terminal one and gives the (E) isomers as the main
## Abstract A clean, facile and practical synthesis of α‐oxoketene __S,S__‐acetals in water has been developed. Catalyzed by tetrabutylammonium bromide (TBAB) at room temperature in water, a range of β‐dicarbonyl compounds have been converted to the corresponding α‐oxoketene __S,S__‐acetals in very