Ibotenic acid stimulates d-[3H]aspartate release from cultured cerebellar granule cells
โ Scribed by Doble, A.; Hubert, J.P.
- Book ID
- 123328515
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 330 KB
- Volume
- 96
- Category
- Article
- ISSN
- 0304-3940
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๐ SIMILAR VOLUMES
The effect of nicotine on basal and electrically evoked (20 Hz for 20 sec) [(3)H]D-aspartate efflux (assumed as an index of transmitter release) was studied in rat cerebellar granule primary cultures. Nicotine (10-100 nM) increased the basal efflux two to three times and concentration-dependently en
Neurotransmitter release in response to either 55 mM K + or 25 pM glutamate as well as its dependency on Ca2' from different sources was compared in cultured glutamatergic cerebellar granule cells from rat brain. The intracellular Ca2+ concentration was monitored at the single cell level in neurites