IARC p53 mutation database: A relational database to compile and analyze p53 mutations in human tumors and cell lines
β Scribed by Tina Hernandez-Boussard; Patricia Rodriguez-Tome; Ruggero Montesano; Pierre Hainaut
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 252 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1059-7794
No coin nor oath required. For personal study only.
β¦ Synopsis
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Mutation of the p53 gene is found in about one third of astrocytic brain tumors, and expansion of tumor cell clones containing mutant p53 has been implicated in astrocytic tumor progression. However, admixture of normal cells in astrocytic tumor specimens limits the power of traditional studies of t
## BACKGROUND. The appearance of p53 mutations in colorectal carcinoma was determined, independent of differentiation and tumor stage of the primary tumors, in relation to the survival of patients who were scheduled to undergo liver resection. ## METHODS. Tumor material was analyzed for p53 mut