The chromosomal assignment of the gene encoding the invariant (Ii) chain associated with the mouse immune response antigens (Ia) was determined by Southern blot analysis of DNA from a panel of mouse x Chinese hamster somatic cell hybrids cleaved with Hind III or Eco RI. Using a mouse Ii cDNA as a hy
✦ LIBER ✦
Ia associated Iichain is not encoded by chromosome 17 of the mouse
✍ Scribed by Norbert Koch; Günter J. Hämmerling; Jacek Szymura; Matthias R. Wabl
- Publisher
- Springer-Verlag
- Year
- 1982
- Tongue
- English
- Weight
- 351 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0093-7711
No coin nor oath required. For personal study only.
✦ Synopsis
Note added in proof
While this manuscript was in preparation we have learned that P. Jones has detected an allelic form of the [ i chain in a particular species of mus. Using this polymorphism and backcross studies Jones and coworkers found also that I i is not encoded by chromosome 17 (P. Jones, personal communication).
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