𝔖 Bobbio Scriptorium
✦   LIBER   ✦

I1307K Adenomatous Polyposis coli gene mutation in colorectal cancer patients with a family history or early onset of colorectal cancer attending a family cancer clinic in London

✍ Scribed by Dove-Edwin, I; Frayling, I; Thomas, HJW

Book ID
123328658
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
171 KB
Volume
114
Category
Article
ISSN
0016-5085

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Mutation analysis of the adenomatous pol
Mutation analysis of the adenomatous polyposis coli (APC) gene in northwest Spanish patients with familial adenomatous polyposis (FAP) and sporadic colorectal cancer
✍ Clara Ruiz-Ponte; Ana Vega; Angel Carracedo; Francisco Barros πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 26 KB πŸ‘ 2 views

Germline mutations in the tumor-suppresor APC gene are associated with hereditary familial adenomatous polyposis (FAP) and somatic mutations are common in sporadic colorectal cancer. In this study, we report the identification of three novel germline mutations: 1682-1683insA, 3252-3253insAT, 3544A>T

Clinical and screening implications of t
Clinical and screening implications of the I1307K adenomatous polyposis coli gene variant in Israeli Ashkenazi Jews with familial colorectal neoplasia : Evidence for a founder effect
✍ Paul Rozen; Tova Naiman; Hana Strul; Philipp Taussky; Nataly Karminsky; Ruth Sho πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 92 KB πŸ‘ 1 views

## Abstract ## BACKGROUND The authors previously found the I1307K adenomatous polyposis coli (__APC__) gene variant in 5% of Ashkenazi control participants, in 15.4% of those who had familial colorectal neoplasia, but also in 1.6% of non‐Ashkenazi control participants. In this study, they evaluate