I. Preparation of [18F]p-fluorophenylhydrazine using diazonium chemistry. II. A radiolabelled glucocorticoid: [18F]WIN 44577

Synthetic studies with [18F]p-fluorobenz

Synthetic studies with [18F]p-fluorobenzenediazonium chloride application to the synthesis of a radiolabelled glucocorticoid: [18F]WIN 44577

✍ Anthony L. Feliu 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 French ⚖ 405 KB

A route was devised to synthesize no-carrier-added or carrier-added C\*uFlp-fluorophenylhydratine from aqueous C'OFlfluoride. Key reaction in this three-step sequence is the reduction o f C1nFlp-fluorobenzenediazonium chloride with sodium cyanoborohydride. The utility of this method is demonstrated