I and i antigens on normal human T and B lymphocytes and on lymphocytes from patients with chronic lymphocytic leukemia
β Scribed by Kenneth H. Shumak; Rose A. Rachkewich; Melvyn F. Greaves
- Book ID
- 118373161
- Publisher
- Elsevier Science
- Year
- 1975
- Tongue
- English
- Weight
- 472 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1090-2341
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## Abstract Lymphocytes, isolated from the peripheral blood of normal persons and patients with chronic lymphocytic leukemia, have been studied for cap formation and agglutinability by Concanavalin A (Con A). Twentyβeight to 32% of the lymphocytes from 12 normal persons formed a cap and there was a
Large granular lymphocytes (LGL) may exert regulatory influences on B cell immunoglobulin synthesis. We, therefore, investigated the influence of LGL from controls and B cell chronic lymphocytic leukemia patients (B-CLL) on control B cell proliferation to costimulation with the F(ab'), fragment of g