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Hypoxia upregulates cyclooxygenase-2 and prostaglandin E2 levels in human peritoneal fibroblasts

✍ Scribed by G.M. Saed; H.M. Abu-Soud; A.R. Munkarah; M.P. Diamond

Book ID
118444163
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
67 KB
Volume
82
Category
Article
ISSN
1556-5653

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## Abstract ## Objective To elucidate the mechanism of basic calcium phosphate (BCP) crystal–induced prostaglandin E~2~ (PGE~2~) production in human foreskin fibroblasts (HFFs), to identify the signaling pathway involved in the induction of cyclooxygenase 2 (COX‐2) messenger RNA (mRNA) by BCP crys