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Hypoxia-Selective Agents Derived from Quinoxaline 1,4-Di-N-oxides

✍ Scribed by Monge, Antonio; Palop, Juan A.; de Cerain, Adela Lopez; Senador, Virginia; Martinez, Francisco J.; Sainz, Yolanda; Narro, Susana; Garcia, Estrella; de Miguel, Carlos

Book ID
119998677
Publisher
American Chemical Society
Year
1995
Tongue
English
Weight
814 KB
Volume
38
Category
Article
ISSN
0022-2623

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## Abstract A problem that confronts clinicians in the treatment of cancer is the resistance of hypoxic tumors to chemotherapy and radiation therapy. Thus, the development of new drugs that are toxic to hypoxic cells found in solid tumors is an important objective for effective anticancer chemother