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Hypoxia inducible factor (HIF)-2α is required for the development of the catecholaminergic phenotype of sympathoadrenal cells

✍ Scribed by Stephen T. Brown; Kevin F. Kelly; Juliet M. Daniel; Colin A. Nurse


Book ID
111181564
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
460 KB
Volume
110
Category
Article
ISSN
0022-3042

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## Abstract ## Objective To uncover the mechanism by which hypoxia enhances cartilage matrix synthesis by human articular chondrocytes. ## Methods The hypoxic response was investigated by exposing normal (nonarthritic) human articular chondrocyte cultures to 20% oxygen and 1% oxygen. Induction o