Nucleus pulposus (NP) cells of the intervertebral disc reside in an environment that has a limited vascular supply and generate energy through anaerobic glycolysis. The goal of the present study was to examine the expression and regulation of HIF-1a, a transcription factor that regulates oxidative m
✦ LIBER ✦
HIF-1α and HIF-2α degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc
✍ Scribed by Nobuyuki Fujita; Kazuhiro Chiba; Irving M Shapiro; Makarand V Risbud
- Book ID
- 112118153
- Publisher
- American Society for Bone and Mineral Research
- Year
- 2012
- Tongue
- English
- Weight
- 280 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0884-0431
- DOI
- 10.1002/jbmr.538
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Nucleus pulposus cells express HIF-1α un
✍
Makarand V. Risbud; Asha Guttapalli; David G. Stokes; David Hawkins; Keith G. Da
📂
Article
📅
2006
🏛
John Wiley and Sons
🌐
English
⚖ 221 KB
Tonicity enhancer binding protein (TonEB
✍
Shilpa S Gogate; Nobuyuki Fujita; Renata Skubutyte; Irving M Shapiro; Makarand V
📂
Article
📅
2012
🏛
American Society for Bone and Mineral Research
🌐
English
⚖ 653 KB
Osmolarity and Intracellular Calcium Reg
✍
Sachin Gajghate; Akihiko Hiyama; Monica Shah; Daisuke Sakai; D Greg Anderson; Ir
📂
Article
📅
2009
🏛
American Society for Bone and Mineral Research
🌐
English
⚖ 919 KB
Up-regulation of hypoxia-inducible facto
✍
Krieg, Marion; Haas, Richard; Brauch, Hiltrud; Acker, Till; Flamme, Ingo; Plate,
📂
Article
📅
2000
🏛
Nature Publishing Group
🌐
English
⚖ 626 KB
Differential regulation of VEGF, HIF1α a
✍
Eva L. Lund; Anja Høg; Minna W.B. Olsen; Lasse T. Hansen; Svend A. Engelholm; Pa
📂
Article
📅
2003
🏛
John Wiley and Sons
🌐
French
⚖ 299 KB
## Abstract We examined how ionizing radiation (IR) delivered under either severe hypoxia (< 0.1% O~2~) or normoxia affects the expression of hypoxia inducible factor 1α (HIF‐1α) and the angiogenic factors vascular endothelial growth factor (VEGF) and angiopoietins 1, 2 and 4 in U87 human glioblast
Chorionic gonadotropin regulates the tra
✍
D. Herr; C. Keck; C. Tempfer; Detlef Pietrowski
📂
Article
📅
2004
🏛
John Wiley and Sons
🌐
English
⚖ 117 KB