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Hypoxia-inducible factor (HIF-1)α: its protein stability and biological functions

✍ Scribed by Lee, Ji-Won; Bae, Seong-Hui; Jeong, Joo-Won; Kim, Se-Hee; Kim, Kyu-Won


Book ID
120560696
Publisher
Korean Society of Medical Biochemistry and Molecular Biology
Year
2004
Tongue
English
Weight
325 KB
Volume
36
Category
Article
ISSN
1226-3613

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## Abstract Quercetin, a ubiquitous bioactive plant flavonoid, has been shown to inhibit the proliferation of cancer cells and induce the accumulation of hypoxia‐inducible factor‐1α (HIF‐1α) in normoxia. In this study, under hypoxic conditions (1% O~2~), we examined the effect of quercetin on the i