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Hypoxia-inducible factor-1α suppresses the expression of macrophage scavenger receptor 1

✍ Scribed by Ken Shirato; Takako Kizaki; Takuya Sakurai; Jun-etsu Ogasawara; Yoshinaga Ishibashi; Takehiko Iijima; Chikako Okada; Izumi Noguchi; Kazuhiko Imaizumi; Naoyuki Taniguchi; Hideki Ohno

Publisher
Springer
Year
2009
Tongue
English
Weight
231 KB
Volume
459
Category
Article
ISSN
0031-6768

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Quercetin suppresses hypoxia-induced accumulation of hypoxia-inducible factor-1α (HIF-1α) through inhibiting protein synthesis
✍ Dae-Hee Lee; Yong J. Lee 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 285 KB

## Abstract Quercetin, a ubiquitous bioactive plant flavonoid, has been shown to inhibit the proliferation of cancer cells and induce the accumulation of hypoxia‐inducible factor‐1α (HIF‐1α) in normoxia. In this study, under hypoxic conditions (1% O~2~), we examined the effect of quercetin on the i