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Hypoxia inducible factor-1α correlates with VEGF-C expression and lymphangiogenesis in breast cancer

✍ Scribed by Sebastian F. Schoppmann; Alexandra Fenzl; Monika Schindl; Thomas Bachleitner-Hofmann; Katalin Nagy; Michael Gnant; Reinhard Horvat; Raimund Jakesz; Peter Birner

Publisher
Springer US
Year
2006
Tongue
English
Weight
317 KB
Volume
99
Category
Article
ISSN
0167-6806

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✍ A. Giatromanolaki; E. Sivridis; C. Simopoulos; A. Polychronidis; K.C. Gatter; A. 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 235 KB

Aims: To investigate the significance of the hypoxia inducible factors HIF-1a and HIF-2a in gallbladder adenocarcinomas and their relation to angiogenesis and to the expression of VEGF, an angiogenic factor transcriptionally regulated by HIFas. Methods: HIF-1a and 2a expression was assessed immunohi