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Hypoxia-induced β-catenin downregulation involves p53-dependent activation of Siah-1

✍ Scribed by Dapeng Wang; Yongxing Wang; Tao Kong; Feiyue Fan; Yongguang Jiang


Book ID
108587086
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
765 KB
Volume
102
Category
Article
ISSN
1347-9032

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## Abstract Heme oxygenase (HO)‐1 is a cytoprotective molecule that is induced during the response to injury. An increase in HO‐1 is an acute indicator of inflammation, and early induction of HO‐1 has been suggested to correlate with severity of injury. While a great deal is known about the inducti