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Hypoxia-induced remodelling of PDE4 isoform expression and cAMP handling in human pulmonary artery smooth muscle cells

✍ Scribed by Jennifer Millen; Margaret R. MacLean; Miles D. Houslay


Book ID
113582622
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
506 KB
Volume
85
Category
Article
ISSN
0171-9335

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## Abstract Sphingosine‐1‐phosphate (S1P), acting through five closely related G‐protein coupled receptors termed S1P~1–5~, has recently emerged as a possible regulator of smooth muscle cell (SMC) physiology with the potential to induce contraction, proliferation and stress fiber formation. In the