## Abstract Hyperglycemia is the hallmark of diabetes mellitus. Poor glycemic control is correlated with increased cardiovascular morbidity and mortality. High glucose can trigger endothelial cell apoptosis by de‐activation of endothelial nitric oxide synthase (eNOS). eNOS was recently demonstrated
✦ LIBER ✦
Hypoxia-induced regulation of nitric oxide synthase in cardiac endothelial cells and myocytes and the role of the PI3-K/PKB pathway
✍ Scribed by Hans Strijdom; Sven O. Friedrich; Suzél Hattingh; Nontuthuko Chamane; Amanda Lochner
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 543 KB
- Volume
- 321
- Category
- Article
- ISSN
- 0300-8177
No coin nor oath required. For personal study only.
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## Abstract Angiogenesis plays a crucial role in tumor growth and metastases. The extent of angiogenesis correlates with the increased invasion and metastasis in a variety of human neoplasms. Vascular endothelial cell proliferation and migration are critical steps in angiogenesis and are regulated