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Hypoxia-driven proliferation of embryonic neural stem/progenitor cells – role of hypoxia-inducible transcription factor-1α

✍ Scribed by Tong Zhao; Cui-ping Zhang; Zhao-hui Liu; Li-ying Wu; Xin Huang; Hai-tong Wu; Lei Xiong; Xuan Wang; Xiao-min Wang; Ling-ling Zhu; Ming Fan

Book ID
111312360
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
524 KB
Volume
275
Category
Article
ISSN
1432-1327

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## Abstract A reliable method to induce neural progenitor/stem cells (NPCs) into dopaminergic (DAergic) neurons has not yet been established. As well, the mechanism involved remains to be elucidated. To induce DAergic differentiation from NPCs, a cytokine mixture (C‐Mix) of interleukin (IL)‐1β, IL‐