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Hypoxia and reoxygenation increased BACE1 mRNA and protein levels in human neuroblastoma SH-SY5Y cells

✍ Scribed by Sufang Xue; Longfei Jia; Jianping Jia


Book ID
116768889
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
207 KB
Volume
405
Category
Article
ISSN
0304-3940

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## Abstract Free cytoplasmic dopamine may be involved in the genesis of neuronal degeneration in Parkinson's disease and other such diseases. We used SH‐SY5Y human neuroblastoma cells to study the effect of dopamine on cell death, activation of stress‐induced pathways, and expression of α‐synuclein