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Hypoxia and Reoxygenation: a Possible Mechanism for Placental Oxidative Stress in Preeclampsia

✍ Scribed by Tai-Ho Hung; Graham J. Burton

Book ID
117697294
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
122 KB
Volume
45
Category
Article
ISSN
1028-4559

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To characterize the role of oxidative stress in cultured rat sinusoidal endothelial cells, we studied the production of superoxide after reoxygenation, the relationship of reduced glutathione (GSH) levels to cell injury, and the protective efficacy of antioxidants. Hypoxia (pO 2 1-2 mm Hg) was achie