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Hypotonic stress induces E-cadherin expression in cultured human keratinocytes

✍ Scribed by Stefan Kippenberger; Stefan Loitsch; Maike Guschel; Jutta Müller; Roland Kaufmann; August Bernd

Book ID
116465154
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
263 KB
Volume
579
Category
Article
ISSN
0014-5793

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Spatially regulated expression of E (epithelial)-and P (placental)-cadherins is crucial for maintaining normal epidermal architecture. In cutaneous squamous cell carcinomas (SCCs), aberrant P-cadherin expression is often observed in ''squamoid'' cancer cells, whereas E-cadherin expression in cancer