Morphometric and biochemical analysis of
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Urs A. Boelsterli; Luis-M. Cruz-Orive; Gerhard Zbinden
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Article
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1984
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Springer-Verlag
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English
โ 429 KB
The administration of nicotine (1 and 4 mg/kg/day, subcutaneously for up to 6 weeks) to male Sprague-Dawley rats first induced a time-and dose-dependent increase in catecholamine (CA) synthesis. This was followed by an increase in endogenous CA levels and in total volume and number of chromaffin cel