𝔖 Bobbio Scriptorium
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Hypothalamic somatostatin may mediate endotoxin-induced fever in the rat

✍ Scribed by M.-T. Lin; W.-N. Uang; L.-T. Ho

Book ID
112275254
Publisher
Springer-Verlag
Year
1989
Tongue
English
Weight
489 KB
Volume
339
Category
Article
ISSN
0028-1298

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Fever was induced in rats with a single i.p. injection of 30 g/kg E. coli endotoxin. The effect of the alcohol leaf extract of Azadirachta indica was investigated in this model. Pretreatment of rats with the leaf extract (125-375 mg/kg) did not significantly reduce endotoxin-induced fever. The recta