Hyporeactivity to mitogens of retroplacental blood lymphocytes in human pregnancy
β Scribed by Masumi Yoshida; Hideharu Kanzaki; Makoto Tokushige; Shigeyasu Sato; Huei-Sheng Wang; Atsushi Uchida; Shinpei Kasakura; Takahide Mori
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 323 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0165-2478
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The importance of calcium in lymphocyte activation is well recognized, but the levels of extracellular ionized free calcium (Ca+ + ) necessary for lymphocyte proliferation via various pathways have not been investigated in detail. We studied the ability of a lectin mitogen (PHA) and a calcium ionoph
## Abstract The reactivity of peripheral blood lymphocytes from patients with advanced malignancy was assessed by mitogenβinduced stimulation of protein synthesis as measured by ^3^Hβleucine incorporation. It was confirmed that the lymphocyte response of patients was depressed. Furthermore, the lym