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Hyporeactivity of mesenteric resistance arteries in portal hypertensive rats

✍ Scribed by Philippe Sogni; Sana Sabry; Richard Moreau; Adrián Gadano; Didier Lebrec; Tuan Dinh-Xuan Anh


Book ID
118567355
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
439 KB
Volume
24
Category
Article
ISSN
0168-8278

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Chronically portal-hypertensive rats show in vitro vascular hyporeactivity in large part mediated by the endothelium-derived vasodilator nitric oxide. We tested whether long-term octreotide treatment (15 micrograms/kg subcutaneously in 5% D/W, 8-hourly) corrects the in vitro vascular hyporeactivity.