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Long-term octreotide treatment prevents vascular hyporeactivity in portal-hypertensive rats

โœ Scribed by CC Sieber; F Lee; RJ Groszmann


Book ID
118686179
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
210 KB
Volume
23
Category
Article
ISSN
0270-9139

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Long-term octreotide treatment prevents
โœ C C Sieber; F Lee; R J Groszmann ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 210 KB

Chronically portal-hypertensive rats show in vitro vascular hyporeactivity in large part mediated by the endothelium-derived vasodilator nitric oxide. We tested whether long-term octreotide treatment (15 micrograms/kg subcutaneously in 5% D/W, 8-hourly) corrects the in vitro vascular hyporeactivity.