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Hypocrellin and hypericin-induced phototoxicity of HL-60 cells: apoptosis or necrosis?

✍ Scribed by A. Miroššay; J. Mojžiš; J. Tóthová; M. Hájiková; A. Lacková; L. Mirossay


Book ID
114306966
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
931 KB
Volume
7
Category
Article
ISSN
0944-7113

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Different patterns of apoptosis of HL-60
✍ Jianping Gong Xun Li; Zbigniew Darzynkiewicz 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 843 KB

Cells of the human promyelocytic HL-60 line, when treated with a variety of antitumor agents in the presence of the protein synthesis inhibitor cycloheximide (CHX), or with CHX alone, rapidly undergo apoptosis ("active cell death"). It is presumed, therefore, that such cells are "primed" to apoptosi