## Abstract As an extension of our recently published work (Mlejnek and Kuglík [2000] J. Cell. Biochem. 77:6–17), the role of caspases in N^6^‐benzylaminopurine riboside (BAPR)‐induced apotosis in HL‐60 cells was evaluated in this study. Here, BAPR‐induced apoptosis was accompanied by activation of
Effects of caspase inhibition on camptothecin-induced apoptosis of HL-60 cells
✍ Scribed by Malcolm A. King; Monica A. Radicchi-Mastroianni
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 973 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0196-4763
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Cells of the human promyelocytic HL-60 line, when treated with a variety of antitumor agents in the presence of the protein synthesis inhibitor cycloheximide (CHX), or with CHX alone, rapidly undergo apoptosis ("active cell death"). It is presumed, therefore, that such cells are "primed" to apoptosi
## Abstract Transcriptional activation of AP‐1 is intricately involved in cell proliferation and transformation. The natural product, nordihydroguaiaretic acid (NDGA) shows an inhibitory effect on the binding of jun/AP‐1 protein to the AP‐1 site in 12‐__O__‐tetradecanoylphorbol‐13‐acetate (TPA)‐sti