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Hyperthermic Killing and Hyperthermic Radiosensitization in Chinese Hamster Ovary Cells: Effects of pH and Thermal Tolerance

✍ Scribed by Eugene V. Holahan, Donald P. Highfield, Patricia K. Holahan and William C. Dewey

Book ID
124662017
Publisher
Bioone
Year
1984
Tongue
English
Weight
810 KB
Volume
97
Category
Article
ISSN
0033-7587

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## Abstract The uptake and metabolism of the polyamines spermine, spermidine, cadaverine and putrescine, previously shown to potentiate heat sensitivity, were studied in cultured Chinese hamster cells. Heat (42Β°C) causes enhanced uptake of exogenously supplied polyamines into the acid‐soluble fract