## Abstract The uptake and metabolism of the polyamines spermine, spermidine, cadaverine and putrescine, previously shown to potentiate heat sensitivity, were studied in cultured Chinese hamster cells. Heat (42°C) causes enhanced uptake of exogenously supplied polyamines into the acid‐soluble fract
✦ LIBER ✦
Enhancement of Thermal Killing by Polyamines: III. Synergism between Spermine and γ Radiation in Hyperthermic Chinese Hamster Cells
✍ Scribed by E. Ben-Hur and E. Riklis
- Book ID
- 124615885
- Publisher
- Bioone
- Year
- 1979
- Tongue
- English
- Weight
- 636 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0033-7587
- DOI
- 10.2307/3575049
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## Abstract Exposure of Chinese hamster cells to polyamines at an elevated temperature (42°C) results in synergistic cell killing. The effectiveness of polyamines in potentiating thermal killing decreases in the following order: spermine>spermidine> cadaverine>putrescine. The magnitude of the syner