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Hyperthermic isolated limb perfusion with cisplatin in four patients with sarcomas of soft tissue and bone

✍ Scribed by Robert J. van Ginkel; Heimen Schraffordt Koops; Elisabeth G.E. de Vries; Willemina M. Molenaar; Donald R.A. Uges; Harald J. Hoekstra

Book ID
117569472
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
347 KB
Volume
22
Category
Article
ISSN
0748-7983

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Hyperthermic isolated limb perfusion for
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Hyperthermic isolated limb perfusion (HILP) with various chemotherapeutic agents has been used for the local treatment of high-grade soft tissue sarcomas (STS) of the extremities, but in most cases, with a disappointing result. Most such regimens certainly should not be considered superior to surger

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## BACKGROUND. Of the different options for limb-sparing treatment for patients with soft tissue limb sarcomas (STLS), hyperthermic antiblastic perfusion (HAP) combined with surgery might be the most effective in terms of tumor resectability, local control, and aesthetic and functional results. Th

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## Background and Objectives: The prognosis for recurrent multifocal limb soft tissue sarcoma (STS) is dismal due to systemic spread. However, many of these patients undergo amputation due to ineffective local control. The purpose of the present study was to determine whether isolated limb perfusi