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Hypersensitivity of ataxia-telangiectasia fibroblasts to a nitric oxide donor

โœ Scribed by Michael H.L Green; Adam J Marcovitch; Susan A Harcourt; Jillian E Lowe; Irene C Green; Colin F Arlett


Book ID
114276434
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
198 KB
Volume
22
Category
Article
ISSN
0891-5849

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Ataxia telangiectasia (AT) cells exhibit greater levels of apoptosis than normal fibroblasts following exposure to X-rays or radiomimetic drugs. In this study, we investigated apoptosis in AT cells whose radiation sensitivity has been altered by transfection with a cDNA expressing truncated IB-โฃ (โŒฌI