Hyperplasia in the spinal sensory system of the frog. I. Plasticity in the most caudal dorsal root ganglion
β Scribed by Miriam R. Davis; Martha Constantine-Paton
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 985 KB
- Volume
- 221
- Category
- Article
- ISSN
- 0021-9967
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An increase in neurotrophic activity for the survival of dissociated sensory neurones has been found in the spinal cord of morphine dependent rats. This activity is not due to morphine itself and is not due to an increase in the nerve growth factor as antibodies to nerve growth factor fail to block
## Abstract Embryonic sensory neurons express membraneβanchored growth factors that stimulate proliferation and differentiation of Schwann cells. The most important of these are members of the neuregulinβ1 (Nrgβ1) family that activate the erbB2/erbB3 receptor kinase on Schwann cells. Nrgβ1 growth f