Hyperkalemic periodic paralysis and paramyotonia congenita – A novel sodium channel mutation –
✍ Scribed by Shiho Okuda; Fumio Kanda; Keisuke Nishimoto; Ryogen Sasaki; Kazuo Chihara
- Book ID
- 106096197
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 493 KB
- Volume
- 248
- Category
- Article
- ISSN
- 0340-5354
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📜 SIMILAR VOLUMES
Paramyotonia congenita (PC), an autosomal dominant non-progressive muscle disorder, is characterised by cold-induced stiffness followed by muscle weakness. The weakness is caused by a dysfunction of the sodium channel in muscle fibre. Parts of the gene coding for the alpha-subunit of the sodium chan
## Abstract The nosological distinction between paramyotonia congenita (PC) and hyperkalemic periodic paralysis (HPP) continues to generate debate. Recently, electrophysiological signs thought to be specific for each entity have been described and have been used to bolster the argument that the two