Hyperkalemic periodic paralysis with cardiac dysrhythmia: A novel sodium channel mutation?
โ Scribed by Jaime L. Baquero; Ricardo A. Ayala; Jianzhou Wang; Dr. Richard G. Curless; W. Gregory Feero; Eric P. Hoffman; Makram R. Ebeid
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 449 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Hyperkalemic periodic paralysis (HPP) is caused by mutations of the adult skeletal muscle sodium channel (SCN4A) gene on chromosome 17. Malignant hyperthermia (MH) is a genetically heterogeneous autosomal-dominant disorder occurring in association with various neuromuscular diseases or without other
Congenital long QT syndrome type 3 (LQT3) is caused by mutations in the gene SCN5A encoding the alpha-subunit of the cardiac Na(+) channel (Nav1.5). Functional studies of SCN5A mutations in the linker between domains III and IV, and more recently the C-terminus, have been shown to alter inactivation