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Hyperhomocysteinemia and deep vein thrombosis in orthotopic heart transplantation: A case report

✍ Scribed by Alex Costea; Geetha Bhat

Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
55 KB
Volume
77
Category
Article
ISSN
0361-8609

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✦ Synopsis

Abstract

Homocysteine has been recognized as a risk factor for atherosclerosis and arterial and venous thrombosis. Heart transplant patients have an increased prevalence of hyperhomocysteinemia. High homocysteine levels in transplant patients may promote development of cardiac allograft vasculopathy, but there is minimal information regarding the risk of venous thrombosis. The current case report illustrates the association of increased levels of homocysteine and hypercoagulable syndrome in a 36‐year‐old heart transplant patient with no previous history of clotting disorder. Both elevated homocysteine levels and extensive venous thrombosis responded promptly to treatment with a folate/B~12~/B~6~ vitamin combination and enoxaparin. Am. J. Hematol. 77:161–163, 2004. Β© 2004 Wiley‐Liss, Inc.

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