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Hyperglycaemia and hyperinsulinaemia: is insulin-degrading enzyme the missing link?

✍ Scribed by J. Fawcett; W. C. Duckworth

Book ID
105819519
Publisher
Springer
Year
2009
Tongue
English
Weight
177 KB
Volume
52
Category
Article
ISSN
0012-186X

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## Abstract Insulin degrading enzyme (IDE) is expressed in the brain and may play an important role there in the degradation of the amyloid beta peptide (AΞ²). Our results show that cultured human cerebrovascular endothelial cells (HCECs), a primary component of the blood–brain barrier, express IDE