Insulin degrading enzyme is localized pr
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John A. Lynch; Ana M. George; Patricia B. Eisenhauer; Kelly Conn; Wenwu Gao; Isa
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Article
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2006
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John Wiley and Sons
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English
β 243 KB
π 1 views
## Abstract Insulin degrading enzyme (IDE) is expressed in the brain and may play an important role there in the degradation of the amyloid beta peptide (AΞ²). Our results show that cultured human cerebrovascular endothelial cells (HCECs), a primary component of the bloodβbrain barrier, express IDE