## Background: The purpose of this study was to determine the feasibility and efficacy of hyperfractionated accelerated radiotherapy (hfrcb) combined with simultaneous chemotherapy with weekly cisplatin (cddp) in locally advanced inoperable head and neck cancer. ## Methods: From august 1999 to de
β¦ LIBER β¦
Hyperfractionated, accelerated chemoradiation with concurrent mitomycin-C and cisplatin in locally advanced head and neck cancer, a phase I/II study
β Scribed by Thomas Hehr; Johannes Classen; Stefan Welz; Ute Ganswindt; Heike Scheithauer; Asen Koitschev; Michael Bamberg; Wilfried Budach
- Book ID
- 118496692
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 141 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0167-8140
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## Background: Both twice daily fractionated radiotherapy and concurrent cisplatin with once-daily radiotherapy have been shown to improve local disease control in patients with head and neck cancer. the objective of this phase i trial was to determine the maximum tolerated dose of cisplatin which