## Background: Both twice daily fractionated radiotherapy and concurrent cisplatin with once-daily radiotherapy have been shown to improve local disease control in patients with head and neck cancer. the objective of this phase i trial was to determine the maximum tolerated dose of cisplatin which
✦ LIBER ✦
Phase I/II docetaxel plus concurrent hyperfractionated radiotherapy in locally advanced unresectable head and neck cancer (TAX.ES1.102 study)
✍ Scribed by Agustí Barnadas; Ricard Mesía; Margarita Majem; Ramón Galiana; Antonio López-Pousa; José M. de Vega; Mireia Margelí; Vicente Valentí; Lluís Anglada; Ariadna Lloansí; Antonio Arellano
- Book ID
- 107597787
- Publisher
- Springer Milan
- Year
- 2011
- Tongue
- Spanish
- Weight
- 182 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1699-048X
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## Abstract ## BACKGROUND Amifostine was developed to protect normal tissues from radiation exposure. The current study was undertaken to determine whether amifostine would allow the delivery of greater numbers of weekly paclitaxel treatments with concomitant, hyperfractionated radiotherapy in pat