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Hyperdiploid acute myeloid leukemia Relationship between blast size and karyotype demonstrated by fluorescence in situ hybridization

✍ Scribed by Y.L. Kwong; K.F. Wong

Book ID: 114136003
Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 435 KB
Volume: 83
Category: Article
ISSN: 0165-4608
DOI: 10.1016/s0165-4608(95)00027-5

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## Abstract Double minute chromosomes (dmin) are small chromatin bodies consisting of genes amplified in an extrachromosomal location. dmins are uncommon in hematologic malignancies; they are seen primarily in acute myeloid leukemia, with amplification of the __MYC__ oncogene or, less frequently, t