The barbier reaction: No organometallic
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Pierre Bauer; GΓ©rard Molle
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Article
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1978
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Elsevier Science
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French
β 194 KB
From the synthesis standpoint, there is renewed interest in the Barbier reaction (I), i.e. condensation between a reagent, A, and a halogenated derivative, RX, in the presence of a metal (magnesium or lithium), M, 1-5 due to the very high yields observed in certain cases. Furthermore, the differenc