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Hyperaggregation of platelets in intestinal tuberculosis: Role of platelets in chronic inflammation

✍ Scribed by Dr. Ravindra Sarode; Deepak Bhasin; Neelam Marwaha; Pallab Roy; Kartar Singh; D. Panigrahi; Gurjeevan Garewal; S. K. Mehta

Publisher: John Wiley and Sons
Year: 1995
Tongue: English
Weight: 252 KB
Volume: 48
Category: Article
ISSN: 0361-8609
DOI: 10.1002/ajh.2830480111

No coin nor oath required. For personal study only.

✦ Synopsis

Eighty-eight percent (38/43) patients of intestinal tuberculosis showed significant hyperaggregation of platelets (P < 0.001). Serum and plasma from 15 patients when incubated with normal platelets caused hyperaggregation. Gel filtered platelets from 2 patients suspended in normal plasma showed hyperaggregation of platelets with arachidonic acid. Tubercular protein had no effect on platelet aggregation. A role of hyperactive platelets in chronic inflammatory response is discussed.

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