Hydroxyurea-induced hemolytic anemia in a patient with essential thrombocythemia
โ Scribed by Fadi I. Jabr; Ali Shamseddine; Ali Taher
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 64 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0361-8609
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Essential thrombocythemia (El) Is an uncommon myeloprollferatlve disorder, which is thought to develop from a multlpotent stem cell. Like other myeloprollferatlve diseases, ET is assoclated with an increased risk of development of acute leukemla (AL). However, the large majority of cases of leukemic
changes in renal function. Proteinuria was reversible after withdrawal of the drug and was reproducible at reexposure. The extent of proteinuria was dose dependent. Renal biopsy revealed a (possibly pre-existing) minimal change glomerulonephritis. Uncovering of an underlying autoimmune defect by IFN