Hydroxyl-directed reductive ring opening at the C-2 position of functionalized 2-aryloxetanes
β Scribed by Thorsten Bach; Christian Lange
- Book ID
- 103407011
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 117 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
## Abstract The title compounds 7 were prepared in situ by deprotection of the corresponding pivaloylβsubstituted oxetanes 3 with lithium aluminium hydride in tetrahydrofuran. under these conditions a reductive ring opening at cβ2 (hydrodealkoxylation) occurred which was initiated by a nucleophilic
Regioselective Reductive Ring Opening of 2-(2-Hydroxyphenyl)-3-(( trimethylsilyl)oxy)oxetanes at the More Substituted C-2 Position. -The title compounds are prepared in situ by deprotection of the oxetanes (III) and (IV) with LiAlH4 in THF. Under these conditions a reductive ring opening occurs yiel