𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Hydroxyindole derivatives as inhibitors of IL-1 generation. I. Synthesis and pharmacological activities of (E)-3-(4-hydroxy-5-methoxyindole-7-yl)-2-methylpropenoic acid derivatives

✍ Scribed by M Tanaka; T Kaneko; H Akamatsu; M Okita; K Chiba; H Obaishi; H Sakurai; I Yamatsu

Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
997 KB
Volume
30
Category
Article
ISSN
0223-5234

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis and Glycosidase Inhibitory Act
Synthesis and Glycosidase Inhibitory Activities of 5-(1′,4′-Dideoxy-1′,4′-imino-D-erythrosyl)-2-methyl-3-furoic Acid (=5-[(3S,4R)-3,4-Dihydroxypyrrolidin-2-yl]-2-methylfuran-3-carboxylic Acid) Derivatives: New Leads as Selective α-L-Fucosidase and β-Galactosidase Inhibitors
✍ Antonio J. Moreno-Vargas; Inmaculada Robina; Raynald Demange; Pierre Vogel 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 German ⚖ 217 KB 👁 1 views

## Abstract The __García‐González__ reaction of D‐glucose and ethyl acetoacetate generated ethyl 5‐[(1′__S__)‐D‐erythrosyl]‐2‐methyl‐3‐furoate (**5**), which was converted to ethyl 5‐[(1′__R__)‐1′,4′‐dideoxy‐1′,4′‐imino‐D‐erythrosyl]‐2‐methyl‐3‐furoate (**3c**) and to ethyl 5‐[(1′__S__)‐1′,4′‐dideo

ChemInform Abstract: Synthesis and Biolo
ChemInform Abstract: Synthesis and Biological Evaluation of [2′-Oxo-2,3-dihydro-3′H-spiro[chromene-4,5′- [1,3]oxazolidin]-3′yl]acetic Acid Derivatives as Aldose Reductase Inhibitors.
✍ Simona Rapposelli; Frederico Da Settimo; Maria Digiacomo; Concettina La Motta; A 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 62 KB 👁 1 views

## Abstract A series of the title spirocyclic benzopyran derivatives (XI) (12 examples) is synthesized, which all prove to be selective inhibitors of aldose reductase (ARL2).

Synthesis and In-vitro Antibacterial Act
Synthesis and In-vitro Antibacterial Activity of 7-(3-Aminopyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Derivatives
✍ Xin Guo; Xiao-Guang Bai; Yi-Liang Li; Zhi-Jiao An; Le-Xing Xu; Li-you Han; Ming- 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 169 KB 👁 1 views

A series of novel 7- (3-aminopyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3carboxylic acid derivatives was designed, synthesized and characterized by 1 H-NMR, MS and HRMS. These fluoroquinolones were evaluated for their in-vitro antibacterial activity against representat