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Hydroxyalkylation of 4,5,6,7-tetrahydroindole with polyfluorocarbonyl compounds as a route to 2-substituted indoles

✍ Scribed by Andrei L. Sigan; Dmitrii V. Gusev; Nikolai D. Chkanikov; Elena Yu. Shmidt; Andrei V. Ivanov; Al’bina I. Mihaleva


Book ID
113929765
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
246 KB
Volume
52
Category
Article
ISSN
0040-4039

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✍ Ouro Adetchessi; Daniel Desor; Isabelle Forfar; Christian Jarry; Jean Michel Leg 📂 Article 📅 1997 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 504 KB

## Abstract The reaction of 2‐amino‐2‐oxazolines with ethoxycarbonyl isocyanate was investigated in order to access to fused 1,3,5‐triazine‐2,4‐diones with a potential 5‐HT~2~ antagonist activity. The reaction leads to 2,3,6,7‐tetrahydro‐4__H__‐oxazolo[3,2‐__a__]‐1,3,5‐triazine‐2,4‐diones and to 1‐