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Hydromorphone analgesia after intravenous bolus administration

โœ Scribed by Barbara Coda; Akira Tanaka; Robert C. Jacobson; Gary Donaldson; C.Richard Chapman


Book ID
117479944
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
240 KB
Volume
71
Category
Article
ISSN
0304-3959

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Pharmacokinetics of hydromorphone after
โœ P. V. Parab; Dr. W. A. Ritschel; D. E. Coyle; R. V. Gregg; D. D. Denson ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 629 KB

The pharmacokinetic properties of hydromorphone in healthy young male subjects were studied after i.v., peroral, and rectal administration. After i.v. administration the following pharmacokinetic parameters were found: elimination half-life 2.36 k 0.5 h, hepatic extraction ratio 0.51, apparent volum