Hydrolytic degradation of porous scaffolds for tissue engineering from terpolymer of l-lactide, ε-caprolactone and glycolide
✍ Scribed by Elżbieta Pamuła; Piotr Dobrzyński; Maciej Bero; Czesława Paluszkiewicz
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 264 KB
- Volume
- 744-747
- Category
- Article
- ISSN
- 0022-2860
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## Abstract Polyblend fibrous scaffolds in mass ratios of 100/0, 90/10, 80/20, and 70/30 from poly(L‐lactide) (PLLA) and poly(ϵ‐caprolactone) (PCL) for cartilage tissue engineering were prepared in three steps: gelation, solvent exchanging, and freeze‐drying. Effects of the blend ratio, the exchang
## Abstract __In vitro__ degradation of seven three‐dimensional porous scaffolds composed of PLGA85/15, a very useful poly(D,L‐lactide‐__co__‐glycolide), was performed in phosphate‐buffered saline solution at 37°C up to 26 weeks, and effects of porosity (80–95%) and pore size (50–450 μm) on the deg
## Abstract Hexaarmed star‐shaped hydroxyl‐terminated poly(ε‐caprolactone) (PCL) was successfully synthesized via the ring‐opening polymerization of ε‐caprolactone (CL) with hexakis[__p__‐(hydroxymethyl)phenoxy]cyclotriphosphazene initiator and stannous octoate catalyst in bulk. The star‐shaped PCL
## Abstract Electrospun composite mats of poly[(D,L‐lactide)__‐co‐__glycolide] and collagen with high porosities of 85–90% and extended pore sizes of 90–130 µm were prepared to mimic the ECM morphologically and chemically. The existence of collagen molecules on the fiber surface was confirmed, enab