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Hydrolytic degradation behavior of biodegradable polyetheresteramide-based polyurethane copolymers

✍ Scribed by CaiBing Liu; YingChun Gu; ZhiYong Qian; LinYu Fan; Jun Li; GuoTao Chao; MingJing Tu; WenJuan Jia


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
125 KB
Volume
75A
Category
Article
ISSN
1549-3296

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✦ Synopsis


Abstract

In this article, a new kind of biodegradable polyetheresteramide‐based polyurethane (PEEA‐U) copolymers were prepared by the melt polycondensation method from ϵ‐caprolactone, 6‐aminocaproic acid, poly(ethylene glycol), and toluene diisocyanate. The water absorption of PEEA‐U was affected strongly by the reaction time and the content of chain extender; and the hydrolytic degradation behavior of the copolymers was mainly determined by the reaction time, chain extender content, and the pH value of the degradation medium. Also, DSC, ^1^H‐NMR, and inherent viscosity were used to characterize the degradation behavior of the copolymers. © 2005 Wiley Periodicals, Inc. J Biomed Mater Res, 2005


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